Guardians of the Genome is a virtual reality (VR) game currently in development. It is designed to teach players about accurate DNA structure and base-pairing through hands-on experiences. Equipped with special tools emulating DNA repair enzymes, players are tasked with fixing common mistakes in DNA called base-pairing errors. Guardians is a fun and immersive way to learn about this fundamental molecule of life.

A prototype of Guardians is available for licensing to select educational groups and events in exchange for feedback and testimonials that AXS can use to guide further development and marketing.

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In development for


360° video
Making of (Coming soon)


How can I play Guardians of the Genome?

  • Guardians is still in development. We do have a prototype available for licensing to select educational groups and events in exchange for feedback and testimonials that AXS can use to guide further development and marketing. Contact us to learn more.
What are the minimum hardware specs to run Guardians of the Genome?

  • Processor: Intel Core i5-4590/AMD FX 8350 equivalent or better
  • GPU: NVIDIA GeForce GTX 1060, AMD Radeon RX 480 equivalent or better
  • Memory: 4 GB RAM or more
  • Video output: HDMI 1.4, DisplayPort 1.2 or newer
  • USB port: 1x USB 2.0 or newer
  • Operating system: Windows 10
What is the timeline for release of Guardians of the Genome?

What VR headsets support Guardians of the Genome?

  • Guardians is being developed for HTC Vive and Oculus Rift.
Who is AXS Studio and why did you create Guardians of the Genome?

  • AXS Studio creates interactive experiences for education in science and medicine. We started Guardian of the Genome to explore science learning with VR — and because we love science, visualization, and gaming! You can learn more about our work at axs3d.com.
Who was Guardians of the Genome designed for?

  • Guardians was designed with high school and undergraduate university students in mind (see Suggested Curriculum Connections); however, our goal was to create an enjoyable experience for any learner, regardless of their age or knowledge of the subject matter.
Why an educational game? Can’t I just learn about DNA in a textbook?

  • Educational games like Guardians allow learners to exercise their creativity, critical-thinking, and problem-solving skills to navigate complex concepts in a safe, immersive environment. Unlike traditional didactic teaching methods, educational games have the unique ability to motivate players by tapping into their intrinsic reward systems and desire to compete with themselves and with their peers. Learners are more engaged and have agency to direct their own learning in creative ways. We believe that Guardians can help students and the general public form a strong fundamental understanding of DNA, empowering and preparing them for a future world where the application of DNA-based technologies is commonplace.


  • Differentiate between the four nitrogenous bases of DNA
  • Demonstrate complementary base pairing
  • Identify the enzymes and processes involved in DNA mismatch repair


SBI4U (Grade 12 University Biology)

  • D2.2 analyse a simulated strand of DNA to determine the genetic code and base pairing of DNA
  • D3.1 explain the current model of DNA replication, and describe the different repair mechanisms that can correct mistakes in DNA sequencing
  • F3.2 explain the structure and functions of macromolecules (e.g., DNA, RNA) and the synthesis of proteins (e.g., transcription, translation, gene expression)




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